Mixed Oxides to Obtain Compounds with Potential Bioactivity: Study of Parameters and Modeling

Abstract

Mixed oxides of Zn, Mg, and Al were synthesized from Layered Double Hydroxides (LDH) with different molar ratios by the coprecipitation method and calcination at 450 °C. The LDH and their oxides were physicochemically characterized to analyze their surface area, crystal structure, morphology, and basic properties. The results show that the LDH have a hydrotalcite-like structure, which changes upon calcination to form their respective oxides. The mixed oxides exhibit a higher surface area and basic sites compared to their precursors. Therefore, they could be used as catalysts in condensation reactions between benzaldehyde and 2,5-dihydroxyacetophenone to form bioactive compounds like flavones. It is proposed to determine the variables to be used in the mathematical modeling of biocompound synthesis processes.